James Guyton

Managing Director
Expertise in performance improvement
Focus on life sciences companies
Works with corporate executives, PE investors, and senior leaders
Washington, D.C.
@alvarezmarsal
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James Guyton is a Managing Director with Alvarez & Marsal Life Sciences in Washington, D.C. He is known for performance improvement in life sciences companies, helping clients improve profitability, drive growth, and deliver products and services to meet patient needs. He specializes in pharmaceuticals, biologics, vaccines, medical devices, diagnostics, contract services, distributors, and digital health.

Mr. Guyton’s expertise includes operating model simplification, organizational transformation, capability development, EBITDA expansion, cost reduction, M&A pre-/post-deal, product development, and portfolio management. His clients include corporate executives, private equity investors, and senior leaders responsible for functional teams.

Mr. Guyton’s client experience includes defining strategy for a future-facing R&D organization for a major pharmaceutical company; reorganizing a pharmaceutical client’s clinical operations group to enable rapid capacity expansion; integrating product development organizations of a post-merger pharmaceutical client for a $40 million EBITDA improvement; driving development of a product strategy for a pharmaceutical client’s $1 billion-a-year product franchise; accelerating development processes for drug and vaccine candidates; and defining G&A cost optimization opportunities for a PE-owned medical diagnostics company.

Additionally, Mr. Guyton has designed an innovative operating model for the quality function of a leading medical products company; led the due diligence for a $1 billion take-private medical device carve-out; led a clean-sheet organizational build for a major medical products distributor to identify cost reduction opportunities; identified opportunities to improve commercial pipeline and optimize production asset utilization for a CDMO; identified SG&A improvement opportunities in due diligence of a $2 billion CRO acquisition target.

Prior to joining A&M, Mr. Guyton was a Managing Director at KPMG Strategy, where he led performance improvement for Healthcare & Life Sciences. Previously, he was a Director at AlixPartners, focusing on private equity. Earlier, he helped grow health sector consulting practices at A.T. Kearney, PwC Advisory and PRTM Management Consultants.

Mr. Guyton earned a bachelor’s degree (Morehead Scholar) from the University of North Carolina at Chapel Hill and a master’s degree in economics and technology management from the Fletcher School at Tufts University.

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